How it works

Application of NINS acts simultaneously on multiple levels:

Perceptual
  • Deep, penetrating warmth
  • Rapid reduction in perceived discomfort
  • Rapid improvement in would appearance
  • Increased threshold for pain
Physical
  • Vasodilatation caused by local creation of nitric oxide
  • Relaxation of muscle spasms
  • Reduction of swelling
  • Accelerated wound healing
  • Increased wound strength
Biological
  • Increased macrophage migration
  • Enhanced fibroblast migration
  • Enhanced collagen deposition
  • Dramatically improved wound tensile strength (100% improvement at 4th post-traumatic day)
  • Increased endorphin production
  • Decreased nerve conduction velocity and raised perception threshold of sensory nerves
  • P2X3 pain receptor blockade
  • Accelerated removal of cellular debris